Metabolic effects of fenfluramine in obese diabetics.
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چکیده
منابع مشابه
Plasma Leptin in Obese Subjects and Diabetics
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Fifty seven newly diagnosed obese maturity onset diabetics were studied for 3 years to monitor the effect of diabetic control on weight and blood lipids. Of the 41 patients who had a satisfactory control of diabetes, weight loss of a modest degrec was recorded in only 6. The blood lipids did not show any significant changes in both the controlled and uncontrolled groups. It is suggested that bl...
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Twenty obese inpatients who claimed to crave carbohydrate-rich foods were given d-fenfluramine (15 mg p.o., twice daily) or its placebo, double-blind, for two consecutive eight-day periods. Food choices were measured on treatment days 1, 7, and 8 by giving the subjects access to unlimited portions of six isocaloric meal foods (three high in carbohydrate and three high in protein) and of 10 iso...
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The fractalkine (CX3CL1-CX3CR1) chemokine system is associated with obesity-related inflammation and type 2 diabetes, but data on effects of Cx3cr1 deficiency on metabolic pathways is contradictory. We examined male C57BL/6 Cx3cr1-/- mice on chow and high-fat diet to determine the metabolic effects of Cx3cr1 deficiency. We found no difference in body weight and fat content or feeding and energy...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1977
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1977.tb00781.x